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Updated: June 5, 2025
Dauboeuf, Garraway, Hemming, Skinner, and Cobner mention roseola and scarlatiniform erythema after minute doses of quinin. In nearly all these cases the accompanying symptoms were different. Heusinger speaks of a lady who, after taking 1/2 grain of quinin, experienced headache, nausea, intense burning, and edema, together with nodular erythema on the eyelids, cheeks, and portion of the forehead.
In one case the pleural cavity was washed out with a five per cent solution of boric acid and was followed by distressing symptoms, vomiting, weak pulse, erythema, and death on the third day. In the second case, in a youth of sixteen, death occurred after washing out a deep abscess of the nates with the same solution. The autopsy revealed no change or signs indicative of the cause of death.
The main calumny is confuted by the fact that no toad has yet been discovered furnished with any teeth whatsoever; but the obnoxious repute still attaches to the milky exudation sometimes perceptible from glands situated on either side behind the head; nevertheless experiments have shown, that though acrid, the secretions of the toad are incapable of exciting more than a slight erythema on the most delicate skins.
The most commonly employed are vinegar, acetic acid, carbolic acid, nitric acid, and carbonate of sodium; but tramps frequently use sorrel and various species of ranunculus. The lesions simulated are usually inflammatory in character, such as erythema, vesicular and bullous eruptions, and ulceration of the skin.
The fact that the skins of most animals are pigmented and covered with hair, precludes the easy detection of erythema by visual examination, consequently this indicator of possible inflammation is not often made use of in the examination of equine subjects. Attitude of the Subject.
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