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Over these, the essential control lies in the pituitary and the thyroid. So we find that pituitary types have, when there is oversecretion, large bony, gross hands, spade-shaped, or when there is undersecretion, hands that are plump, with peculiarly tapering fleshy fingers. The hyperthyroid has long slender fingers, the subthyroid pudgy, coarse, ugly foreshortened hands, often cold, and bluish.
There are losses of balance, so that when one gland ceases secreting, another will simultaneously or soon after. Normal secretion, oversecretion or undersecretion are thus adjusted, but leave a train of after effects. So with loss or insufficiency of the thyroid, there may be pituitary overgrowth, because the pituitary may act as vicar for the thyroid.
An abnormal process in the anterior gland, whether of oversecretion or of undersecretion, may interfere with the proper functioning of the posterior gland, the secretion of which is tonic not only to the brain cells, but also to the sex cells. Thus, young animals deprived of the pituitary will not, if male, grow spermatozoa, nor ripe ova in the female.
These, like human covenants, vary with the different reactions of the parties to the contract. And so a great deal depends upon whether they work harmoniously or discordantly, and upon which does the most work and which the least. Undersecretion and Oversecretion
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