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Railroads, those vitalizing nerve-fibers of commerce, are so scarce along this division of the border that even in this day when we boast, or lament, that we no longer have a frontier, there remain in Texas sections larger than some of our Eastern states which hear the sound of iron wheels only on their boundaries.

Exsection of the brachial plexus was performed, but gave only temporary relief. The man died in his eighty-fourth year of senile debility. According to Osler the tubercula dolorosa or true fascicular neuroma is not always made up of nerve-fibers, but, as shown by Hoggan, may be an adenomatous growth of the sweat-glands.

Under the microscope these tumors showed an increase in the interfascicular as well as perivascular fibers, but the nerve-fibers were not increased in size or number. Virchow collected 30 cases of multiple neurofibromata. In one case he found 500, in another from 800 to 1000 tumors.

This change, as I have seen in my practice of medicine, sometimes passes up the nerves toward the centers, and occasions a more or less constant irritation of the nerve-fibers, producing neuralgia, which is usually referred by the brain to that part of the lost limb to which the affected nerve belonged.