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It bears certain analogies to Raynaud's disease in that spasm of the vessels plays a part in determining the local death. The main arteries are narrowed by hyperplastic endarteritis followed by thrombosis, and similar changes are found in the veins.
Diabetic coma; uræmia. Status lymphaticus. This is a general hyperplastic condition of the lymphatic structures in the body, and is seen in enlargement of tonsils, thymus, spleen, as well as of Peyer's patches and mesenteric glands. It is a frequent cause of death during chloroform anæsthesia for slight operations in young people.
It consists of approximately equal parts of glycerin, alcohol and distilled extract of witch hazel, to which is added liquor cresolis compositus, two percent, and coloring matter q.s. Complete resolution does not occur in the average case. There remains some hyperplastic tissue and even where the enlargement is slight, the prominent situation of the affection precludes its being unnoticed.
On the other hand, if the brain remains vigorous, the kidneys may take the strain and break down; if the kidneys do not break, the blood-vessels may harden; if the blood-vessels are not affected, the thyroid may become hyperplastic and produce Graves' disease; if the thyroid escapes, diabetes may develop; while if the iron constitution of the mechanism can successfully bear the strain in all its parts, then the individual will break his competitors, and their mechanisms will suffer in the struggle.
A suppurating cartilaginous quittor, complicated by the presence of a large amount of hyperplastic tissue, cannot be successfully represented to be an acute and recently developed affection, where a trained practitioner is left to judge the validity of the statement.
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