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The tree, known at present by the name of Bonplandia trifoliata, grows at the distance of five or six leagues from the eastern bank of the Carony, at the foot of the hills that surround the missions Capapui, Upata and Alta Gracia. The Caribbee Indians make use of an infusion of the bark of the cuspare, which they consider as a strengthening remedy.

Nevertheless, the men of colour, and particularly the Creole negroes, resist much better than any other race, the influence of the climate. Lemonade and infusions of Scoparia dulcis are given to the sick; but the cuspare, which is the cinchona of Angostura, is seldom used.

M. Bonpland recognised the cuspare in the vegetation of the gulf of Santa Fe, situated between the ports of Cumana and Barcelona. The sickly traveller may perchance repose in a cottage, the inhabitants of which are ignorant of the febrifuge qualities of the trees that shade the surrounding valleys.

I hope that the botanical determination of the bark-tree of New Andalusia will one day fix the attention of travellers, who visit this region after us; and that they will not confound, notwithstanding the analogy of the names, the cuspa with the cuspare. The latter not only vegetates in the missions of the Rio Carony, but also to the west of Cumana, in the gulf of Santa Fe.