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Updated: May 14, 2025
Very complex chemically, “biogen” is able to operate upon the circulating or reserve “nutritive” materials in a way comparable, for instance, to the action of “nitric acid in the production of English sulphuric acid.” That is to say, it is able to set up processes of disruption and of recombination, apparently by its mere presence, but, in reality, by its own continual breaking down and building up again.
Starting from this basis, he analyses and rejects the explanations which have been offered in terms of the analogy of ferments, enzymes, or catalytic processes. In particular, he disputes Ostwald’s “Energismus” and Verworn’s Biogen hypothesis.
The most recent of these hypotheses is that set forth by Verworn in his book “Die Biogenhypothese.” He assumes, as the central vehicle of the vital functions, a unified living substance, the “biogen,” nearly related to the proteids which form the fundamental substance of protoplasm and of the cell-nucleus, and in contrast to which the other substances found in the living body are in part raw materials and reserves, and in part of a derivative nature, or the results of disruptive metabolism.
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