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Updated: May 29, 2025
Darier has reported that a single subconjunctival injection of a milligram of iodate of sodium has cleared the cornea and lessened the intra-ocular pain in glaucoma. What shall be said in regard to certain medicinal agents which stimulate the lymphagogue activity of the eyeball in their relation to the reduction of intra-ocular tension, notably of dionin?
This hypothesis also might suggest why the subconjunctival injection of sodium citrate in addition to alkalinizing the ocular contents, may be effective in reducing tension, i. e., the amount of fluid injected beneath conjunctiva may overcome the stagnation in the lymph passages, flush out these channels and improve ocular elimination.
In compression of the brain, fracture of the skull may be present, subconjunctival hæmorrhages may be seen, the pupils are unequal and dilated, and the paralysis increases. In uræmic or diabetic coma the urine must be examined. The habitual use of opium is not uncommon, and opium-eaters are able to take enormous quantities of the drug.
To be sure, myotics were also used, but these myotics were insufficient, totally so in the two instances noted prior to the enteroclysis. Very interesting are the observations on the subconjunctival injections of various substances, notably the citrate of sodium, because of its power of decreasing the affinity of ocular colloids for water.
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