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I cannot think that anybody who has systematically used dionin with holocain, the former in gradually increasing strength, beginning with 2 per cent and going up to 8 per cent, in various types of acute glaucoma, particularly of the secondary variety, can fail to have noted a favorable influence.

He believes that dionin not only does not reduce the tension but hinders the filtration through the anterior lymph channels by the pressure of the edema which is produced on the veins and by the increased secretion of the ciliary processes.

Darier has reported that a single subconjunctival injection of a milligram of iodate of sodium has cleared the cornea and lessened the intra-ocular pain in glaucoma. What shall be said in regard to certain medicinal agents which stimulate the lymphagogue activity of the eyeball in their relation to the reduction of intra-ocular tension, notably of dionin?

They use various derivatives of opium, like morphine and heroin, also codeine, dionin, narcein, ethyl chloride and bromide, nitrite of amyl, amylin, and the skill that they have acquired in the manipulation of these powerful drugs stamps them as the most dangerous coterie of criminals in existence.