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Updated: May 8, 2025


When pregnancy does not occur the corpus luteum is formed, but begins to diminish within ten or twelve days in the human species and is then gradually absorbed. According to O'Donoghue, in the Marsupial Dasyurus there seems to be no difference either in the development of the milk glands or of the corpora lutea between the pregnant and the non-pregnant animal. Lin.

Bruno Wolff, from experiments on bitches, concluded that the central nervous system in women is probably more easily excited in the pregnant than in the non-pregnant state, though he was not prepared to call this cerebral excitability "specific." Direct observations on pregnant women have shown, without doubt, a heightened nervous irritability. Reflex action generally is increased.

This has been frequently mentioned by authors as leading to enlargement of the uterus in the non-pregnant condition; and it is a still more potent factor in the recently impregnated organ, whose tissues are succulent and the vessels enlarged, a condition inviting congestion and enhancing the susceptibility to engorgement.

In one experiment ovaries from a pregnant rabbit were implanted into the peritoneum of a non-pregnant rabbit, but on post-mortem examination of the latter eleven days later the implanted ovaries were found to be necrosed and no proliferation of milk gland had taken place.

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