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Hughes gives an excellent description of the clinical aspect of arthritis which applies here: Acute arthritis begins like an ordinary attack of synovitis. In joints other than the pedal and pastern, there is sudden and extensive swelling, which at first is intra-articular, succeeded by extra-articular tumefaction, and accompanied by violent lameness. The pain soon becomes intense and agonizing.

The treatment is carried out on the same principles as in other pyogenic infections. The limb is immobilised in such an attitude that should stiffness occur there will be the least interference with function. Extension by weight and pulley is the most valuable means of allaying muscular spasm and relieving intra-articular tension and of counteracting the tendency to flexion; as much as 15 or 20

Intra-articular ligaments, such as the ligamentum teres in the hip, are usually worn away and disappear. The surrounding muscles undergo atrophy, tendons become adherent to their sheaths and may be ossified, and the sheaths of nerves may be involved by the cicatricial changes in the surrounding tissues.

The infection may spread to the adjacent joint, either directly through the epiphysis and articular cartilage, or along the deep layer of the periosteum and its continuation the capsular ligament. When the epiphysis is intra-articular, as, for example, in the head of the femur, the pus when it reaches the surface of the bone necessarily erupts directly into the joint.