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In the year 1852 he became aware of the presence of a calculus, but not until 1872 did he ask for medical assistance. He explained that he had introduced a chisel through his perineal fistula to the stone, and attempted to comminute it himself and thus remove it, and by so doing had removed about an ounce of the calculus.
Now this paste must be pressed to the bottom of all the orifices; if very deep it must be made sufficiently thin to inject by means of a small syringe, and repeated once in two days, until the callous pipes, and hard fibrous base around the poll evil, or fistula, is completely destroyed. Sometimes one application has cured cases of this kind, but it will generally require two or three.
He was celebrated for his successful surgical treatment of fistula lacrymalis, and while at Genoa invented for use in connexion with the operation the fine-pointed syringe still known by his name.
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