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From four to six drops were sufficient to destroy a man; and it was asserted, that the dose could be so proportioned as to operate in a certain time. Labat says, that Tofania distributed her poison in small glass phials, with this inscription Manna of St. Nicholas of Bavi, and ornamented with the image of the saint.

That prepared by Tofania appears to have been a clear insipid water, and the sale of aqua fortis was for a long time forbidden in Rome, because it was considered the principal ingredient. This, however, is not probable. Haller was of this last opinion. In the casket of St.

By means of a crafty female their practices were detected; the whole society were arrested and put to the torture, and the old woman, whose name was Spara, and four others, were publicly hanged. This Spara was a Sicilian, and is said to have acquired her knowledge from Tofania at Palermo. Tophania, or Tofania, was an infamous woman, who resided first at Palermo and afterwards at Naples.

This decision would not of course, diminish the suspicion already excited; and among other physicians, who were consulted on the case, M. Lodin, professor of Medicine at Lynkoping, presented two memoirs, in which he stated it as his opinion, that a slow poison of a vegetable nature, and probably analogous to the aqua tofania, had been administered to the Prince, and that this had caused the apopletic fit of which he died.