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Updated: May 29, 2025
In general, the hydrogen addition products were found to be more active than the simple base, an observation entirely in accord with the theory formed by Wischnegradsky, and by Konigs, as the result of the study of the decomposition products of the alkaloids, viz., the alkaloids are in general hydrogen addition products of pyridine and quinoline, or of the two bases combined. Thus Prof.
These compounds had a very surprising febrifuge action, without any unpleasant after effects or local disturbances. The most active workers in the field of synthetic formation of the alkaloids have been Wischnegradsky, of St. Petersburg who, unfortunately for science, died at an untimely age in 1880 Königs and Fischer, of Munich, and Ladenburg, of Kiel.
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