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Updated: May 16, 2025
Smith and Schuster found that castration at other seasons caused the pad to remain in the condition in which it was at the time, that there was no reduction or absorption as Nussbaum and Meisenheimer found, and that allo-transplantation of testes that is, the introduction of testes from other frogs either into the dorsal lymph-sacs or into the abdominal cavity or the injection of testis extract, had no effect in causing growth or development of the thumb-pad.
It seems impossible that the horny layer or its papillae could atrophy in consequence of castration, or be absorbed. Meisenheimer claims that he produced development of papillae on the thumb-pad, not only by implantation of pieces of testis, but also by implantation of pieces of ovary.
Meisenheimer and Kopee after him claim to have grafted ovaries into males and testes into females, with the result that the transplanted organs remained alive and grew, and in some cases at least became connected with the genital ducts.
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