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C. Section of a nerve trunk. 1. Epineurium consisting chiefly of connective tissue. 2. Bundles of nerve fibers. 3. Covering of fiber bundle, or perineurium. 4. Small artery and vein. The side-by-side arrangement of the neurons shows clearly the structure of the ganglia and nerves.
The connective-tissue framework of a nerve-trunk consists of the perineurium, or general sheath, which surrounds all the bundles; the epineurium, surrounding individual groups of bundles; and the endoneurium, a delicate connective tissue separating the individual nerve fibres. The blood vessels and lymphatics run in these connective-tissue sheaths.
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