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Updated: May 19, 2025
Syphilitic sequestra are heavier and denser than normal bone, because sclerosis usually precedes death of the bone. The bones especially affected by gummatous disease are: the skull, the septum of the nose, the nasal bones, palate, sternum, femur, tibia, and the bones of the forearm. In the bones of the skull, gummata may form in the peri-cranium, diploë, or dura mater.
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