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On the 11th of August, 1492, after the lingering death-agony of Innocent VIII, during which two hundred and twenty murders were committed in the streets of Rome, Alexander VI ascended the pontifical throne. Son of a sister of Pope Calixtus III, Roderigo Lenzuoli Borgia, before being created cardinal, had five children by Rosa Vanozza, whom he afterwards caused to be married to a rich Roman.

But Roderigo Borgia, having corrupted the rest of the college, assumed the mantle of S. Peter in 1492, with the ever-memorable title of Alexander VI. Roderigo was the son of Isabella Borgia, niece of Pope Calixtus III., by her marriage with Joffré Lenzuoli. He took the name of Borgia, when he came to Rome to be made Cardinal, and to share in his uncle's greatness.

On the 11th of August, 1492, after the lingering death-agony of Innocent VIII, during which two hundred and twenty murders were committed in the streets of Rome, Alexander VI ascended the pontifical throne. Son of a sister of Pope Calixtus III, Roderigo Lenzuoli Borgia, before being created cardinal, had five children by Rosa Vanozza, whom he afterwards caused to be married to a rich Roman.

Of Alfonso Borgia, who reigned for three years as Calixtus III., little need be said, except that his pontificate prepared for the greatness of his nephew, Roderigo Lenzuoli, known as Borgia in compliment to his uncle. The last days of Nicholas had been imbittered by the fall of Constantinople and the imminent peril which threatened Europe from the Turks.