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Each landscape became a pale vision: bush and grass and flower, like spun yarn seen in a fever, the people who passed by, and the clouds fibrillated above the forests were of one and the same constituency. Nothing was tangible; the palate lost its sense of taste, the finger its sense of touch. Bad weather was welcome; it subdued the noises, made men quieter.
The transformation of this temporary granulation tissue into scar tissue is effected by the fibroblasts, which become elongated and spindle-shaped, and produce in and around them a fine fibrillated material which gradually increases in quantity till it replaces the cell protoplasm.
If the chronic inflammation is not superimposed on an acute endocarditis there may be no cell infiltration and therefore no softening, but there is a tendency to develop a fibrillated structure, and a fibroid thickening of the endocardium occurs, especially around the valves.
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