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The parents of these unfortunate persons were perfectly healthy, as were the rest of their family. Cruveilhier cites a case of a girl of eleven who had absolutely no cerebellum, with the same symptoms which are characteristic in such cases.

The pupils and successors of Corvisart Bayle, Andral, Bouillaud, Chomel, Piorry, Bretonneau, Rayer, Cruveilhier and Trousseau brought a new spirit into the profession. Everywhere the investigation of disease by clinical-pathological methods widened enormously the diagnostic powers of the physician.

Cruveilhier, who died in 1874, is still remembered by his great work on pathological anatomy; his work on descriptive anatomy has some things which I look in vain for elsewhere.

Cruveilhier, who died in 1874, is still remembered by his great work on pathological anatomy; his work on descriptive anatomy has some things which I look in vain for elsewhere.

Combettes reports the case of a girl who died at the age of eleven who had complete absence of the cerebellum in addition to other minor structural defects; this was probably the case mentioned by Cruveilhier. Diminution in volume of the head is called microcephaly. Probably the most remarkable case on record is that mentioned by Lombroso.