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Updated: July 12, 2025
If the cause of syphilis had not been known, and the disease not given to animals, the discovery of salvarsan might never have been made. After extensive experiments on syphilitic rabbits, which showed that the drug could be given safely in amounts large enough to cure the animal at a single dose, it was tried on man, two physicians, Drs. Hoppe and Wittneben, volunteering for the test.
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