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Updated: May 22, 2025
The amount of glycogen in the liver was diminished in all the experiments showing brain-adrenal activity; and when the histologic changes were repaired, the normal amount of glycogen was again found. In crossed circulation experiments changes were found in the liver of the animal whose brain received the stimulus.
Histologic studies were made of every tissue and organ in the body. Three organs, the brain, the adrenals, and the liver, and these three only, showed histologic changes. In these three organs the histologic changes were marked, and were almost wholly repaired by one seance of sleep. This clear-cut insomnia experiment corresponds precisely with our other brain-adrenal observations.
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