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Updated: May 28, 2025
This caseous material is surrounded by the thickened capsule which, as a result of peri-adenitis, tends to become adherent to and fused with surrounding structures, and particularly with layers of fascia and with the walls of veins. The caseated tissue often remains unchanged for long periods; it may become calcified, but more frequently it breaks down and liquefies.
In the early stages the gland is enlarged, it may be to many times its natural size, is normal in appearance and consistence, and as there is no peri-adenitis it is easily shelled out from its surroundings. On microscopical examination, however, there is evidence of infection in the shape of bacilli and of characteristic giant and epithelioid cells.
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