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Nearly all the Portuguese inhabitants suffer from enlargement of the spleen, the effects of frequent intermittents, and have generally a sickly appearance. Thinking that this affection of the hand was simply an effort of nature to get rid of malarious matter from the system, I recommended the use of quinine.

As far as I have been able to observe, the periods of inflammatory diseases observe the solar day; as the gout and rheumatism have their greatest quiescence about noon and midnight, and their exacerbations some hours after; as they have more frequently their immediate cause from cold air, inanition, or fatigue, than from the effects of lunations: whilst the cold fits of hysteric patients, and those in nervous fevers, more frequently occur twice a day, later by near half an hour each time, according to the lunar day; whilst some fits of intermittents, which are undisturbed by medicines, return at regular solar periods, and others at lunar ones; which may, probably, be owing to the difference of the periods of those external circumstances of cold, inanition, or lunation, which immediately caused them.

Happily their number was small, and in most cases their natures innocent. By these means Elnathan had acquired a certain degree of knowledge in fevers and agues, and could talk with judgment concerning intermittents, remittents, tertians, quotidians, etc.

I am not certain that my testimony will convince any one save myself, but I know that I had rather have my present definite, positive belief based on this evidence, than to be floundering on doubts and uncertainties. There is no doubt that the profession believe that intermittents have a cause; but this belief has a vagueness which cannot be represented by drawings or photograph.

It runs in a deep glen, the sides of which are almost five hundred yards of slope, and rocky, the rocks being hardened calcareous tufa lying on clay shale and sandstone below, with a capping of ferruginous conglomerate. The scenery would have been very pleasing, but fever took away much of the joy of life, and severe daily intermittents rendered me very weak and always glad to recline.

Hence quartan agues are formed in those of this temperament, as explained in Section XXXII. on diseases from irritation, and other intermittents are liable to recur from slight causes many weeks after they have been cured by the bark.

L. D.-The bark of the branches of this tree manifests a considerable degree of bitterness to the taste, and is also astringent; hence it has been thought a good substitute for the Peruvian bark, and, upon trial, was found to stop the paroxysms of intermittents: it is likewise recommended in other cases requiring tonic or astringent remedies.

Mr Banks and Dr Solander recovered slowly at their country-house, which was not only open to the sea breeze, but situated upon a running stream, which greatly contributed to the circulation of the air: But I was now taken ill myself; Mr Sporing, and a seaman who had attended Mr Banks, were also seized with intermittents; and, indeed, there were not more than ten of the whole ship's company that were able to do duty.

Mudiacoro: also an external caustic, and used internally. Kapande: another ordeal plant, but used to produce 'diaphoresis'. Karumgasura: also diaphoretic. Munyazi yields an oil, and is one of the ingredients for curing the wounds of poisoned arrows. Uombue: a large root employed in killing fish. Kakumate: used in intermittents.

The autumnal fevers to which our country towns are subject, in the place of those "agues," or intermittents, so largely prevalent in the South and West, were already beginning, and Maurice, who had exposed himself in the early and late hours of the dangerous season, must be expected to go through the regular stages of this always serious and not rarely fatal disease.