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Nitrous oxide is too transient to be of much use, but to the extent of twenty or thirty gallons may be used with pleasant effect and about five minutes of alleviation. Very different from these powerful agents is the humble, much-neglected scutellaria.

GRATIOLA officinalis. HEDGE-HYSSOP. Herb. E. D. The leaves have a very bitter disagreeable taste: an infusion of a handful of them when fresh, or a dram when dried, is said to operate strongly as a cathartic. Kramer reports that he has found the root of this plant a medicine similar in virtue to Ipecacuanha. Similar Plants. Lythrum Salicaria; Scutellaria galericulata. HELLEBORUS niger.

The pebbly fragments of the entire slope, which during spring-time were sparingly covered with dwarfish herbs, such as the Androsace occidentalis, Draba Caroliniana, Plantago Virginica, Scutellaria parvula, are now crowded with plants of taller growth and variegated blossoms.

The greatest variety of opinions prevails upon the subject of cannabis and scutellaria. The principal objection to the cannabis lies in two facts. First, it is very difficult to obtain any two consecutive specimens of the same strength, even from the same manufacturer.

Cannabis should always be used with caution, but ten or even twenty drops must be inert in all but the rarest cases, and I have given an ounce per diem with beneficial effect. The vast diversity of operation exhibited in different patients by the drug scutellaria is still another illustration of the careful study of idiosyncrasies requisite for a successful treatment of the opium disease.