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Many embryological investigations were performed during the eighteenth century, but most relate to the controversy regarding epigenesis and preformationism as the true expression of embryonic development. Withal, the seventeenth-century embryologists, and particularly the embryologists of seventeenth-century England, had contributed much to the progress of the discipline.
For even as the studies of Mayow were in progress, embryology was embarked upon a course leading to preformationism. By the end of the seventeenth century, the idea that the embryo was encased in miniature in either egg or sperm was elevated to a position of Doctrine, and thereafter there was little encouragement to quantitative study of development.
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