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The tumours, however, after a while diminish in size; the heat and redness diminish; the ulcer partly or entirely closes, but, after a while, and especially when the next period of oestrum arrives, the tumour again increases, and with far greater rapidity than before, and then comes the necessity of the removal of the tumour, or if not, the destruction of the animal.

With regard to the female, it is mostly connected with the secretion of milk. Two or three years may pass, and at almost every return of the period of oestrum, there will be some degree of enlargement or inflammation of the teats. Some degree of fever also appears; but, after a few weeks have passed away, and one or two physic balls have been administered, everything goes on well.

Owing to their lethargic disposition, young Bulldogs are somewhat liable to indigestion, and during the period of puppyhood it is of advantage to give them a tablespoonful of lime water once a day in their milk food. Many novices are in doubt as to the best time to breed from a Bull bitch, seeing that oestrum is present before she is fully developed.

French writers do not hesitate at all upon this point, but even assert that it is very difficult to take a she-wolf with male dogs during the period of oestrum, parceque la veulent saillir et covrir comme une chienne. Baudrillart, in the "dictionaire des chasses," further remarks that the mongrels produced by this connection are very viciously disposed and inclined to bite.

If it is connected with oestrum, the bitch will probably become a disgusting, as well as dangerous animal; if with parturition, there is a strange perversion of maternal affection she is incessantly and violently licking her young, continually shifting them from place to place; and, in less than four-and-twenty hours, they will be destroyed by the reckless manner in which they are treated.

White has been bitten by the oestrum of Shakspearian pronunciation that he becomes thoroughly contradictory of himself, especially after he has taken up the notion that "Much Ado about Nothing" is "Much Ado about Noting," and that the th was not sounded in the England of Shakspeare. After that, his theory of rhetorical variety seems to become that of Geoffroy, "dire, redire, et se contredire."

It is impossible for anyone devoted to the study of "Paradise Lost," of "Comus," even of "Sampson Agonistes," and especially of "Il Pensoroso" and "L'Allegro," to doubt that their writer was carried away at times by the oestrum, or divine afflatus, although Dr Johnson discredits "these bursts of light, and involutions of darkness, these transient and involuntary excursions and retrocessions of invention."

Little can be done to regulate the period of oestrum; but the most valuable breed will be almost invariably that which is produced during the spring, because at that time there will often be opportunity for that systematic exercise on which the growth and powers of the dog so materially depend.

In process of time, however, the period of oestrum is attended by a greater degree of fever and enlargement of the teats, and at length some diminutive hardened nuclei, not exceeding in size the tip of a finger, are felt within one of the teats. By degrees they increase in size; they become hard, hot, and tender. A considerable degree of redness begins to appear.

26th That singular secretion of milk, to which the bitch is subject nine weeks after oestrum, is now appearing. Her mammae are enlarged, and I can squeeze a considerable quantity of milk out of the teats. Give an aloetic pill, and continue the strychnia. 31st. The secretion of milk continues. There is slight enlargement and some heat of the mammae; but she feeds as well as ever.