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Fragments of stone, coal, or metal may lodge in the tissues, and favour the occurrence of infective complications. All such injuries are to be treated on the general principles governing contused and lacerated wounds.

When the organisms become active in this way, the tuberculous tissue undergoes softening and disintegration, and the infective material, by bursting into an adjacent vein, may enter the blood-stream, in which it is carried to distant parts of the body. In this way a general tuberculosis may be set up, or localised foci of tuberculosis may develop in the tissues in which the organisms lodge.

The pathognomonic symptom of open stifle joint is the profuse escape of synovia, indicating perforation of the synovial capsule; by means of a probe the wound may be explored in a way that will clearly reveal the nature of the injury. After a few days have elapsed in cases where considerable infection has taken place, there is manifestation of pain as in all cases of infective arthritis.

They present the appearance of well-defined circular or ovoid areas in which the skin is thickened and raised above the surface; they are covered with a white sodden epidermis, and furnish a scanty but very infective discharge.

The reaction of his fellow-citizens was that by entering the ship he might have become contaminated by blueskin infective material if the plague still existed, and if the men in the ship had caught it but they certainly hadn't died of it and if there had been blueskins on Orede to communicate it for which there was no evidence and if blueskins were responsible for the tragedy.

Where infective wounds of muscles of locomotion occur, the course and gravity of the affection are directly influenced by the proximity of the injury to lymph plexuses. For instance, injuries causing an infectious inflammatory involvement of the adductors of the thigh may result in a generalization of the infection by way of the inguinal lymph glands.

A subacute or a chronic infective endocarditis should be treated on the same plan as an acute endocarditis, which means rest in bed and whatever medication seems advisable, depending on the supposed cause of the condition. A chronic endocarditis which is part of a general arteriosclerosis requires no special treatment except that directed toward preventing the advance of the general disease.

The climatic conditions in some localities favor these occurrences but they may also be ascribed to improper food constituents and to possible infective agencies. Rarefying degenerative changes manifested by exostosis involving the phalanges of the young, causing ringbone, are fairly common in occurrence throughout this country.

It also occurs in relation to the peripheral veins, but in these it can seldom be recognised as a separate entity, being merged in the general infective process from which it takes origin.

In the malignant form the infection is probably more serious or the infective germs are more active, the ulcerations deeper, and the likelihood of emboli and the seriousness of such embolic infarcts more serious and more dangerous.