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To which I demur, questioning why it should be so, and get for answer the two following: III. Every man who does not take our prepared calomel, as prescribed by us in our Constitution and By-Laws, is and must be a mass of disease from head to foot; it being self-evident that he is simultaneously affected with Apoplexy, Arthritis, Ascites, Asphyxia, and Atrophy; with Borborygmus, Bronchitis, and Bulimia; with Cachexia, Carcinoma, and Cretinismus; and so on through the alphabet, to Xerophthahnia and Zona, with all possible and incompatible diseases which are necessary to make up a totally morbid state; and he will certainly die, if he does not take freely of our prepared calomel, to be obtained only of one of our authorized agents.

This will always retain its place in operative surgery as a palliative and life-saving operation for carcinomatous stenosis of the lower part of the colon, and in cases of carcinoma of the rectum in which operation is not feasible.

As it resembles an adenoma in structure it is sometimes described as a malignant adenoma. Its malignancy is shown by the proliferating epithelium invading the other coats of the stomach or intestine, and by the development of secondary growths. Glandular carcinoma originates in organs such as the breast, and in the glands of mucous membranes and skin.

III. Every man who does not take our prepared calomel, as prescribed by us in our Constitution and By-Laws, is and must be a mass of disease from head to foot; it being self-evident that he is simultaneously affected with Apoplexy, Arthritis, Ascites, Asphyxia, and Atrophy; with Borborygmus, Bronchitis, and Bulimia; with Cachexia, Carcinoma, and Cretinismus; and so on through the alphabet, to Xerophthalmia and Zona, with all possible and incompatible diseases which are necessary to make up a totally morbid state; and he will certainly die, if he does not take freely of our prepared calomel, to be obtained only of one of our authorized agents.

In this collection there was an adult heart in which the foremen ovale remained open until the age of thirty-seven; there were but two pulmonary valves; there was another heart showing a large patent foramen ovale from a man of forty-six; and there was a septum ventriculorum of an adult heart from a woman of sixty-three, who died of carcinoma of the breast, in which the foremen ovale was still open and would admit the fore-finger.

Warren pictures a case of noli-me-tangere, a destructive type of epithelial carcinoma. The patient suffered no enlargement of the lymphatic glands. The same absence of glandular involvement was observed in another individual, in whom there was extensive ulceration.

In a boy of thirteen Storrs has reported fracture of the femur within the acetabulum. In addition to the causes enumerated, inflammation of osseous tissue, or osteoid carcinoma, has been found at the seat of a spontaneous fracture. One of the most interesting subjects in the history of surgery is the gradual evolution of the rational treatment of dislocations.

An excessive and erratic growth of epithelium is the essential and distinguishing feature of these tumours. The innocent forms are the papilloma and the adenoma; the malignant, the carcinoma or cancer.

Small polypi may be treated by torsion or astringents. If cut, there is likely to be a subsequent abortion. Large polypi removed toward the close of pregnancy will cause hemorrhage. Carcinoma of the cervix should be removed at once. A few of the examples on record of operations during pregnancy of special interest, will be given below.

There are injuries which set up carcinoma of the mind, we know, cancer spots confined to a small area at first, but gradually extending with infinite pain until all the surrounding healthy tissue is more or less involved, and the whole beautiful fabric is absorbed in the morbid growth, for which there is no certain palliative in time, and no possible prospect of cure except in eternity.