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When nearly sixty years of age, in 1592, she made a second visit to Oxford, where, having been entertained with orations, disputations, etc., she pronounced on her departure, a Latin oration to the vice-chancellors and doctors, when she took her last farewell of the university. In the ensuing year she translated from Latin into English, Boethius's "De Consolatione Philosophæ."

Quae singula cum ad horam pascant vana delectatione sensus corporeos, miseriam tamen inserunt piae menti, quod tot et tanti homines, neglecta prorsus animi salute, his diabolicis operationibus se dederunt in toto. Nam certo non ita sine daemonum consolatione et familiaritate praemissa confingi dicerem.

He painted a most beautiful altar-piece, very finely designed, for S. Francesco, and another for a church called S. Maria "de Consolatione," at the commission of a gentleman of the house of Baciadonne: in which picture he painted the Nativity of Christ, a work that is much extolled, but it was placed in a position so dark, that, by reason of the light not being good enough, one is not able to recognize its perfection, and all the more because Perino strove to paint it in a dark manner, so that it has need of a strong light.

The Craft Lovers was written in the year of our Lord, 1348, and probably the Remedy of Love was written about that time, or not long after. The Lamentation of Mary Magdalen taken from Origen, was written by him in his early years, and perhaps Boethius de Consolatione Philosophiæ was translated by him about the same time.

Early in 45 Cicero lost his beloved daughter Tullia. He passed the whole year in retirement, trying to soothe his grief by incessant writing. In quick succession appeared De Consolatione, an attempt to apply philosophy to the mitigation of his own sorrow and that of others;

Let us condense the story from King Alfred's Anglo-Saxon version of Boethius's De Consolatione Philosophiae: "There was once a famous Thracian harper named Orpheus who had a beautiful wife named Eurydice. She died and went to hell. Orpheus longed sorrowfully for her, harping so sweetly that the very woods and wild beasts listened to his woe.

"We told your lordship in our secret epistle of this morning, written with our ain hand, in testimony we have neither pretermitted nor forgotten your faithful service, that we had that to communicate to you that would require both patience and fortitude to endure, and therefore exhorted you to peruse some of the most pithy passages of Seneca, and of Boethius de Consolatione, that the back may be, as we say, fitted for the burden This we commend to you from our ain experience.

Whether Albinus, Boethius, and Symmachus did plot to bring in Justin; whether the senate did send a letter to him, I cannot tell. Boethius, in his De Consolatione, denies it all; and Boethius was a good man. He says that the letters in which he hoped for the liberty of Rome were forged; how could he hope for the impossible? but he adds, 'would that any liberty could have been hoped for!

He published also about this period the treatise on Judicial Astrology, and the Essay De Consolatione, the only one of his books which has been found worthy of an English translation. In 1541 he became Rector of the College of Physicians, but there is no record of any increase in the number of his patients by reason of this superadded dignity.

Among the books he translated or edited were The Handbook, a collection of extracts on religious subjects; The Cura Pastoralis, or Herdsman's book of Gregory the Great, with a preface by himself which is the first English prose; Bede's Ecclesiastical History of the English; The English Chronicle, which, already brought up to 855, he continued up to the date of writing; it is probably by his own hand; Orosius's History of the World, which he adapted for English readers with many historical and geographical additions; the De Consolatione Philosophiæ of Boethius; and a translation of some of the Psalms.