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Just when he was called to Avignon we do not know, though when the black death ravaged that city in 1348 he was the body-physician of Pope Clement VI, for he is spoken of in a Papal document as "venerabilis et circumspectus vir, dominus Guido de Cauliaco, canonicus et præpositus ecclesiæ Sancti Justi Lugduni, medicusque domini Nostri Papæ."
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