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The author excludes syphilis, tuberculosis, rheumatism, gout, hemophilia, etc., and considers it to have been a trophic affection of cerebral origin. Cases of pneumonia osteoarthropathy simulating acromegaly have been reported by Korn and Murray. Megalocephaly, or as it was called by Virchow, leontiasis ossea, is due to a hypertrophic process in the bones of the cranium.
This rare affection was described by Virchow, and named leontiasis ossea because of the disfigurement to which it gives rise.
History has, indeed, transmitted to us some of the customs of the Numidians, who were by turns, the enemies, and the allies of the Romans; but it has not condescended to draw their portrait. Juvenal somewhere speaks of the withered hands of the Moors: manus ossea Mauri. But, besides, that this is general in hot countries, this description may be understood of ill-fed slaves.
The entire cranium, including the face, is covered with a thick layer of sinter, which gives it the appearance of belonging to the class of skulls with Leontiasis ossea. It is, in fact, of good size, but through the incrustation it is increased to gigantic proportions. It is true, likewise, that it has a much flattened, broad and compressed form.
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