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About noon on Thursday a vesicle formed on the pink surfaces containing clear serum. In the night between Thursday and Friday, usually between midnight and one o'clock, the flow of blood began, the vesicle first rupturing. The amount of blood lost during the so called stigmata varied, and some observers estimated it at about one and three-quarter pints.

We then find that the adipose tissue is made up of two kinds of vesicles: some, bright yellow and transparent, are filled with oily drops; the rest, opaque and starch-white, are distended with a very fine powder, which spreads in a cloudy trail when the vesicle containing it is broken on the object-slide.

The auscultory organ of most of the Invertebrates has substantially the same composition. It usually consists of a closed vesicle, filled with fluid, and containing otoliths, with the acoustic nerve expanding on its wall. But, while the auditory vesicle is usually of a simple round or oval shape in the Invertebrates, it has in the Vertebrates a special and curious structure, the labyrinth.

With its currents it conveys heat away from the torrid zone, and ice from the frigid; or, bottling the caloric away in the vesicle of its vapour, it first makes it impalpable, and then conveys it by unknown paths to the most distant parts of the Earth.

4th. How soon does the arcola arrive at its greatest height in those countries? The arcola surrounding the vaccine vesicle is, I think, at its greatest height about the eleventh or twelfth day after vaccination, if the lymph used has been genuine. 5th. Does small-pox prevail there? 6th. Does small-pox prevail there after vaccination?

In this way is formed at each side, directly under the horny plate of the back part of the head, a small vesicle filled with fluid, the primitive auscultory vesicle, or the primary labyrinth. The outer part of it is lengthened into a thin stem, which at first still opens outwards by a narrow canal.

But how do these propositions agree with our observations on the developmental history of the Crustacea? "The ovarian eggs of all animals are identical, small cells with vitellus, germinal vesicle and germinal spot."

Few persons feel any anxiety from the impossibility of determining at what precise period in the development of the individual, from the first trace of a minute germinal vesicle, man becomes an immortal being; and there is no greater cause for anxiety because the period cannot possibly be determined in the gradually ascending organic scale. The Rev.

On coition, the semen being received into the female organs, which are at that time in a state of turgescence, the spermatozoa, by means of their own vibratile activity, find their way into the Fallopian tubes, and here come in contact with the ovule. The ovule is a minute cell with a transparent membrane, within which is the yolk containing the germinal vesicle.

All these parts of the external and middle ear belong to the apparatus for conducting sound. Their chief task is to convey the waves of sound through the thick wall of the head to the inner-lying auscultory vesicle. They are not found at all in the fishes. In these the waves of sound are conveyed directly by the wall of the head to the auscultory vesicle.