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Filehne found that hydrochlorate of tetrahydroquinoline was much more energetic in its action than quinoline, but could not be used on account of a too powerful local effect. The hydrochlorate of dimethyl-tetrahydroquinoline, which was distinguished by its strong bitter taste, much resembling that of quinine, had an effect like that of curare poison.
When cinchonine is treated with potassium hydrate, it is decomposed into quinoline and a solid body, which on further treatment yields a liquid base, C H N, which is probably lutidine. It has been found, moreover, that both tetrahydroquinoline and dihydroquinoline, hydrogen addition products of quinoline, are present.
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