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"Beginning with this, one disorder followed another in the political struggles between the plebeians and the popular party and the major and minor trades. "After many balias had been appointed for the reformation of the government and there had been two general assemblies of the people, a new government was formed, controlled by the opposition. They recalled all people banished by Sylvestro.

Cardan writes at length to show that the mysterious knocking which he and Rodolfo Sylvestro had heard during his imprisonment at Bologna, the peasant who entered his bed-chamber saying "Te sin casa," and divers other manifestations, going back as far as 1531 croaking of ravens, barking of dogs, and the ignition of fire-wood must all have been brought about by the working of this powerful spirit.

He also received into his house a new pupil, a Bolognese youth named Rodolfo Sylvestro, who was destined hereafter to bring as great credit to his teacher's name in Medicine as Ferrari had already brought thereto in Mathematics.

Rodolfo proved to be one of the most faithful and devoted of friends; he remained at Bologna as long as Cardan continued to live there, sharing his master's ill-fortune, and ultimately accompanied him to Rome in 1571. He gives the names of two other Bolognese students, Giulio Pozzo and Camillo Zanolino, but of all his surviving pupils he rates Sylvestro as the most gifted.

The danger, whatever its nature, seems to have threatened him as a member of the practising faculty at Rome rather than as the persecuted ex-teacher of Pavia and Bologna. Rodolfo Sylvestro was not the only one of his former associates near him in his old age, for he notes that Simone Sosia, who had been his famulus at Pavia in 1562, was still in his service at Rome.

He speaks of a bond which he gave for eighteen hundred gold crowns; and says that, while he was in hold, all his estate was administered by the civil authorities. Rodolfo Sylvestro was constantly with him during his incarceration, and on January 1, 1571, he was released, just at nightfall, and allowed to return to his own house.