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Aortic disease, on the other hand, from the very fact of their strenuous life and occupations, is nearly three times more frequent in men than in women. If a chronic endocarditis has followed an acute condition, some slight permanent papillomas or warty growths may he left from the healed granulating or ulcerated surfaces.
In the papillomas of the skin commonly known as warts the covering consists of epidermis; in those growing from mucous surfaces it consists of the epithelium covering the mucous membrane. When the surface epithelium projects as filiform processes, the tumour is called a villous papilloma, the best-known example of which is met with in the urinary bladder.
Papillomatous growths are also met with in the larynx, in the ducts of the breast, and in the interior of certain cystic tumours of the breast and of the ovary. Although papillomas are primarily innocent, they may become the starting-point of cancer, especially in persons past middle life and if the papilloma has been subjected to irritation and has ulcerated.
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