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The consequences of Koch's important discovery become daily more apparent, and their application more practicable. By JAMES H. SALISBURY, A.M., M.D. Observations in Washington, D. C., September 5, 1879, 8:35 A.M., Boston time, near Congressional Cemetery. Seized with sneezing on my way to cemetery. Examined nasal excretions and found no Palmellae. Pool near cemetery.

I made five observations in like manner about the marshes and bogs of this town, which is, as it were, situated on the tendo achillis of Cape Cod, Mass. In only one of these observations did I find any palmellae like the ague plants, and they were not characteristic. Chelsea, Mass., near the Naval Hospital, September 5, 1877. Three sets of observations.

I found a plenty of the Oscillatoreaceae, but no Palmellae. In September I revisited the city, taking with me a medical gentleman who, residing in the South, had had a larger experience with the disease than I. From the macroscopical examination he pronounced a case we examined to be ague, but I was not able to detect the plants either in the urine or blood.

Found the area abundantly supplied with palmellae, Gemiasma rubra, verdans, and Protuberans lamella, even where there was no incrustation or green mould. Made very many examinations, always finding the plants and spores, giving up only when both of us were overcome with the heat. Observation 34. August, 1881. Visited the Wallabout; found it filled up with earth. August 17.

First Studies to find in their natural habitat the palmellae described as the Gemiasma rubra, Gemiasma verdans, Gemiasma plumba, Gemiasma alba, Protuberans lamella. Second Outfit. Glass slides, covers, needles, toothpicks, bottle of water, white paper and handkerchief, portable microscope with a good Tolles one inch eyepiece, and one-quarter inch objective.

Gemiasma verdans found abundantly with many other things, which if rehearsed would cloud this story. Observation 24. Scrapings from the dirty end of the stick gave specimens of the beautiful double wall palmellae and some empty G. verdans. Observation 25.

I found all the varieties of the palmellae you described in the boxes, and I kept them for several years and demonstrated them as I had opportunity. You also showed me on this visit the following experiments that I regarded as crucial: 1st. I saw you scrape from the skin of an ague patient sweat and epithelium with the spores and the full grown plants of the Gemiasma verdans. 2d.

Observation. Lexington, Mass, September 6, 1877. Observation made in a meadow. There was no saline incrustation, and no palmellae found. No local malaria. Observation. Cambridge, Mass. Water works on the shore of Fresh Pond. Found a few palmellae analogous to, but not the ague palmellae. Observation. Woburn, Mass, September 27, 1877, with Dr. J. M. Moore. Found some palmellae, but scanty.

We say "so-called" advisedly, for in the Algae are included the largest forms of plant life. The Macrocystis pyrifera, an Algae, is the largest of all known plants. It is a sea weed that floats free and unattached in the ocean. At the same time its structure on examination shows it to belong to the same class of plants as the minute palmellae which we have been studying.