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In rare instances the synovial membrane presents nodular masses or lumps, resembling the tuberculous tumours met with in the brain; they project into the cavity of the joint, are often pedunculated, and may give rise to the symptoms of loose body.
It occupied a dollar-sized area above the nape of the neck, and in twelve years reached the length of 12 feet. There was no history of its manner of onset. Tinea nodosa is a name given by Morris and Cheadle to a case of nodular growth on the beard and whiskers of a young man.
While in the nodular stage the affection is sometimes painful, but with the formation of the ulcer the pain subsides. The disease runs a chronic course, and may slowly extend over a wide area in spite of the usual methods of treatment. After lasting for some months, or even years, however, it may eventually undergo spontaneous cure.
The rock is the same nodular conglomerate which is found at so many places, from the seacoast to a distance of 600 miles up the Amazons. Mr. Leavens made a last attempt here to engage men to accompany us to the Araguaya, but it was in vain; not a soul could be induced by any amount of wages to go on such an expedition. The reports as to the existence of cedar were very vague.
Gryllacris lithanthraca, Goldenberg. Professor Goldenberg published, in 1854, descriptions of no less than twelve species of insects from the nodular clay-ironstone of Saarbruck, near Treves. Professor Goldenberg showed me, in 1864, the wing of a white ant, found low down in the productive coal-measures of Saarbruck, in the interior of a flattened Lepidodendron.
This bacillus has all the staining, morphological, and even growth characteristics of the tubercle bacillus except that it produces only local irritation and little nodular masses, if injected into animals.
It is the case of the calcedony agate, containing a body of calcareous spar; here it is to be shown, that, while the calcareous body was altogether inclosed within the calcedony nodular body, these two substances had been perfectly soft, and had mutually affected each others shape, in concreting from a fluid state.
These are the agates, calcedonies, calcareous and zeolite nodules, which are found produced in our whin-stone or subterraneous lavas, that is, the amygdaloides of Crondstedt. Naturalists explain the formation of those nodular bodies differently.
In man also the clinical features of the chronic variety of the disease are somewhat different from those of the acute form. Here, too, infection takes place through a broken cutaneous surface, and leads to a superficial lymphangitis with nodular thickening of the lymphatics (farcy buds). The neighbouring glands soon become swollen and indurated. The primary lesion meanwhile inflames, suppurates, and, after breaking down, leaves a large, irregular ulcer with thickened edges and a foul, purulent or bloody discharge. The glands break down in the same way, and lead to wide destruction of skin, and the resulting sinuses and ulcers are exceedingly intractable. Secondary deposits in the subcutaneous tissue, the muscles, and other parts, are not uncommon, and the nasal mucous membrane may become involved. The disease often runs a chronic course, extending to four or five months, or even longer. Recovery takes place in about 50
Usually they occur as massive or nodular limestones, underlaid by a fine shale or flag-stone; and in other cases, as in the noted Denbighshire sandstones, as a coarse grit of very great thickness. This grit forms mountain ranges through North and South Wales, and is generally marked by the great sterility of the soil where it occurs.
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