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The effect of the inoculation is to make one have real typhoid for a few hours, after that there is a quick recovery, and the absence of typhoid among the men subsequently spoke volumes for the efficacy of the preventative.
The encouragement it gave to inoculation led Queen Caroline to beg six condemned criminals for experiment, and then to submit her own children to that operation. Through its encouragement Bradley accomplished his great discovery, the aberration of the fixed stars, and that of the nutation of the earth's axis; to these two discoveries, Delambre says, we owe the exactness of modern astronomy.
It is true that there was small pox in the City, and among the prisoners at Danville; but that any consideration for our safety should have led them to order general inoculation is not among the reasonable inferences. But, be that as it may, vaccination was ordered, and performed.
Trye says: "I inoculated ten children with matter taken at one time and from the same subject. I observed no peculiarity in any of them previously to their inoculation, nor did any thing remarkable appear in their arms till after the decline of the disease. Two infants of three months old had erysipelas about the incisions, in one of them extending from the shoulders to the fingers' ends.
Nothing was said so I could only suppose that they failed to check us up as it was not in keeping with the German character as we had come to know it to miss any opportunity of corrective punishment even though the inoculation had been for our own good. It is true that some of the men so inoculated fell prey to consumption.
Davaine did, indeed, perform some experiments in inoculation that were successful, but his results were contradicted by the experiments of Messrs. Jaillard and Leplat, and those of Mr. Bert concerning the toxic influence of oxygen at high tension upon microbes. As Davaine was unable to explain the contradiction between his results and those of Messrs.
But some human diseases do not attack animals, and in the case of diseases that may be given to animals it is frequently uncertain whether the disease produced in the animal by such inoculation is identical with the human disease in question, owing to the difference of symptoms in the different animals.
On the other hand, other conditions will cause an increase in the virulence of a pathogenic germ. The virus which produces hydrophobia is increased in violence if it is inoculated into a rabbit and subsequently taken from the rabbit for further inoculation.
See, too, that the place where they have been kept is thoroughly cleansed and sprinkled with lime, for the disease is contagious and the slightest particle of virus will spread it anew. Farcy is but one stage of this terrible disease, but is not necessarily fatal while in this stage. It should, however, be treated with great care and caution. Farcy can also be conveyed to others by inoculation.
How can a sane man forgive himself for advocating inoculation by disease germs to cause immunization when by the use of health germs the health could be built so strong that the pathogenic germs would have no show.
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