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Marie regards the disease as a systemic dystrophy analogous to myxedema, due to a morbid condition of the pituitary body, just as myxedema is due to disease of the thyroid. In several of the cases reported the squint and optic atrophy and the amblyopia have pointed to the pituitary body as the seat of a new growth of hypertrophy. Pershing shows a case of this nature.

As in ordinary œdema, the condition is relieved by elevation of the limb, but not nearly to the same degree; in time the tissues become so hard and tense as scarcely to pit on pressure; this is in part due to the formation of new connective tissue and hypertrophy of the skin; in advanced cases there is a gradual transition into one form of elephantiasis.

More than any other part of the sexual apparatus in either sex, the lesser lips, on account of their shape, their position, and their structure, are capable of acquired modifications, more especially hypertrophy and elongation. By stretching, it is stated, a labium can be doubled in its dimensions.

So a cold climate, which necessitates a more voluminous hair covering for an animal, will evoke a hypertrophy of the adrenal cortex. Secondarily other effects appear as by-products of the adaptation. The adrenal cortex makes for pugnacity, temper, animal courage, irritability and anger reactions. The same applies to woman.

Its origin is said to date back to a semimythical hero of King Arthur's time, who, "when sad at heart and melancholic," would let one of his lips drop below his waist, while he turned the other up like a cap on his head. Blot records a case of monstrous congenital hypertrophy of the superior lip in an infant of eight months.

They are to be distinguished from such over-growths as are of the nature of simple hypertrophy or local giantism, and also from inflammatory swellings, which usually develop under the influence of a definite cause, have a natural termination, and tend to disappear when the cause ceases to act. The etiology of tumours is imperfectly understood.

If the heart is enlarged from hypertrophy, if it is the right ventricle that is the most hypertrophied, the apex is not only pushed to the left, but the beat may be rather diffuse, as the enlarged right ventricle will prevent the apex from acting close to the surface of the chest.

While I received various answers, the chief one was to the effect that the alleged hypertrophy of sex in its gross pathological forms, and the conviction of the kind and degree of sex consciousness found in the many hundreds of analyzed cases, are so unique and constitute the very essence of the neurotic and psychotic cases, and conscious and unconscious sex factors are slight or absent in most normal cases, that these patients and their doctors alike are sex-intoxicated, and that the Freudian psychology applies only to perverts and erotomania or other abnormal cases.

If I take two potatoes, one goes to the elaboration of mental processes, the other to the support of the physical economy. The pauper has only a physical economy, and he needs but one potato. Anemia is the normal condition of the pauper. He breathes comfortably an atmosphere which would give a healthy man asphyxia. Hearty food produces inflammatory diseases and a general condition of hypertrophy.

The modern way of curing neurasthenia is very strange, being neither more nor less than the substitution of hypertrophy of the ego for a disease of the ego! Why not bleed their egoism, or restore the circulation of the blood from head to heart, if they do not have too much, by some violent, moral reagent!