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Posey had a case of coloboma in the macular region in a patient who had a supernumerary tooth. He believes the defects were inherited, as the patient's mother also had a supernumerary tooth. Nunnely reports cases of congenital malformation in three children of one family. The elder sister had the same congenital condition, but to a lesser degree.
In three generations twelve members of one family had either coloboma iridis or irideremia. He performed two operations for the cure of cataract in two brothers. The operations were attended with difficulty in all four eyes and followed by cyclitis. The result was good in one eye of each patient, the eye most recently blind.
We all know that Thomas Henderson maintains that the results of iridectomy are beneficial because the raw edges of the coloboma, which do not cicatrize, permit access of the aqueous to the iris veins, and that myotics, inasmuch as they contract the pupil, open the iris crypts and therefore act, less efficiently, perhaps, but act none the less like an iridectomy.
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