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He altogether rejected Cassanate's view as to the retention of the noxious humours in the head. The Archbishop had the ruddy complexion of a man in good health, a condition which could scarcely co-exist with the loading of the brain with matter which would certainly putrify if retained for any long time.

The Archbishop was irate with his ordinary medical attendant, probably the physician who was left in charge during Cassanate's absence and this man retaliated upon Cardan for having thus stirred up strife. Cardan's position was certainly a very uneasy one.

In the interval of time between Cassanate's first letter to Cardan and the end of 1551, the Regent had half promised to surrender his office into the hands of the Guise party in Scotland, wherefore it was no wonder that the Primate, recognizing how grave was the danger which threatened the source of his power, should have resolved that, sick or sound, his proper place was at the Scottish Court.

Andrews, requesting him to make the journey to Paris, and there to meet the Archbishop, who was suffering from an affection of the lungs. The fame of Cardan as a physician had spread as far as Scotland, and the Archbishop had set his heart on consulting him. Cassanate's letter is of prodigious length.

Moreover, Hamilton writes somewhat querulously about Cassanate's absence abroad on a visit to his family, a fact which would make him all the more eager to secure Cardan's services.

He found Cassanate's treatment too closely fettered by his theory as to the causes of periodic asthma, but he did not venture to exhibit his own course of treatment till after he had gained some knowledge of the Archbishop's temper and habits.

In Cassanate's first letter Paris had been named as the place of meeting; but, as a concession to Cardan's convenience, Lyons was added as an alternative, in case he should find it impossible to spare time for a longer journey. Cardan accordingly halted at Lyons, but neither Archbishop nor physician was there to meet him.