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The erratic Brown-Séquard pounded and hammered away for more than thirty years on the importance to life of the adrenal glands, since death occurred so quickly after their removal. As the upshot, a number of other significant properties besides the first of blood-pressure raising, have been put down to its credit. Chemical tests demonstrated that it originated in the medulla.
But Brown-Séquard remained unshaken. He had all the roués of Paris running to him, and consequent charges of quackery and charlatanism. How much of these unsavory epithets really applied to him will not be determined until we have a better acquaintance with his more intimate life. A biography and collection of his letters is needed.
To conclude, then: the inheritance of an acquired peculiarity in the experiments of Brown-Séquard can be explained by the effect of a toxin on the germ. The lesion, however well localized it seems, is transmitted by the same process as, for instance, the taint of alcoholism. But may it not be the same in the case of every acquired peculiarity that has become hereditary?
Neither could he tell positively whether it was this treatment or the baths which he afterwards took at Aix-les-Bains that finally cured him. His own calm temperament and firmness of mind may have contributed to this as much as Dr. Brown-Sequard. When Sumner returned to Boston, early in 1860, all his friends went to Dr.
Brown-Sequard, Dr., on the inheritance of the effects of operations by guinea-pig. Bruce, on the use of the elephant's tusks. Brulerie, P. de la, on the habits of Ateuchus cicatricosus; on the stridulation of Ateuchus. Brunnich, on the pied ravens of the Feroe islands. Bryant, Dr., preference of tame pigeon for wild mate. Bryant, Captain, on the courtship of Callorhinus ursinus.
Brown-Sequard, then the most distinguished specialist of his day, and Dr. Brown-Sequard, when he arrived and examined his patient, discovered that she had a tumor on the brain. She had had a great shock in her life the tragic death of her husband at sea during their wedding tour around the world and it was believed that her disease dated from that time.
By experiments, not on lightning, which can not be commanded at pleasure, but on the same natural agency in a manageable form, that of artificial galvanism. Dr. Brown-Séquard galvanized the entire bodies of animals immediately after death. Galvanism can not operate in any of the modes in which the stroke of lightning may have operated, except the single one of producing muscular convulsions.
Brown-Sequard gives the following summary of his observations on guinea-pigs, and this summary is so important that I will quote the whole: "'1st. Appearance of epilepsy in animals born of parents having been rendered epileptic by an injury to the spinal cord. "'2nd. Appearance of epilepsy also in animals born of parents having been rendered epileptic by the section of the sciatic nerve. "'3rd.
He hastened to Paris, was appointed, and lived, in spite of the most erratic of existences, to the ripe old age of 78, working up to the last minute. Addison's monograph stimulated Brown-Séquard, in the year after its printing, to reproduce the fatal disease experimentally by excising the suprarenal capsules in animals. Addison was very modest in his monograph.
By cutting the spinal cord or the sciatic nerve of guinea-pigs, Brown-Séquard brought about an epileptic state which was transmitted to the descendants. Lesions of the same sciatic nerve, of the restiform body, etc., provoked various troubles in the guinea-pig which its progeny inherited sometimes in a quite different form: exophthalmia, loss of toes, etc.
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