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Among lesions of the viscera, mention should be made of gumma of the testis, which causes the organ to become enlarged, uneven, and indurated. This has even been observed in infants a few months old.

The evolution of it can only be explained either on the theory of mutation or some Lamarckian hypothesis. The process of dislocation of the testis does not conform to the conception of mutation, nor agree with other cases of that phenomenon. A mutation is a change of structure affecting more or less the whole soma, but showing itself especially in some particular organ or structure.

The more highly the injured part is endowed with sensory nerves the more marked is the shock; a crush of the hand, for example, is attended with a more intense degree of shock than a correspondingly severe crush of the foot; and injuries of such specially innervated parts as the testis, the urethra, the face, or the spinal cord, are associated with severe degrees, as are also those of parts innervated from the sympathetic system, such as the abdominal or thoracic viscera.

The facts concerning cryptorchidism, that is to say, failure of the descent of the testes in Mammals, seem to show that the hormone of the testis is not derived from semen or spermatogenesis, for in the testes which have remained in the abdomen there is no spermatogenesis, while the interstitial cells are present, and the animals in some cases exhibit normal or even excessive sexual instinct, and all the male characteristics are well marked.

The rhyming inscription round the arch of the canopy is, Sis testis Xte quod non tumulus iacet iste corpus ut ornetur, sed spiritus ut memoretur. The "Virginia Inn" at the cross-road is said to be the spot where Sir Walter Raleigh's servant emptied a stoup of beer over his master, who was smoking, in the belief that he was on fire. A field is still said to bear the name of the Priory Plot.

Sometimes he lays the gland +upon+ the outside of the human testis, connecting part with part; sometimes he opens the testis by incision and lays the goat-gland within the cleft. Very often there are adhesions which must be broken down before the goat-gland can function rightly.

It is this physiological change which causes the development of female secondary characters. He describes this change as the production of a hermaphrodite sexual formative substance, on the ground that in at least one case eggs were found in the testis of a male Inachus which had been the host of a Sacculina, but had recovered.