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The changes supposed to take place in the Graafian follicles at each menstrual period were believed to involve a peculiar expenditure of nerve force, which was so much dead loss to the individual life of the woman. The growth of the Graafian vesicle and its contained ovum was supposed to cause an irritation of the nerves of the ovary, which was reflected to the entire nervous system.

Its effects fall as far short of what might have been expected from its virulence as the pearly vaccine vesicle falls short of the terrors of the confluent small-pox. They might with as much propriety call them matricides, if they did not agree with the milder teachings of their mothers. I can imagine Jonathan Edwards in the nursery with his three-year-old child upon his knee.

With all, as far as is at present known, the germinal vesicle is the same; so that all organisms start from a common origin. If we look even to the two main divisions namely, to the animal and vegetable kingdoms certain low forms are so far intermediate in character that naturalists have disputed to which kingdom they should be referred.

This fibrous envelope takes the form of a closed round vesicle, surrounding the whole of the ball and pushing between the lens and the horny plate at its outer side. The round wall of the capsule soon divides into two different membranes by surface-cleavage. The inner membrane becomes the choroid or vascular coat, and in front the ciliary corona and iris.

If a doctor be careful which, of course, he will be to take the matter from a healthy child, and from a well-formed vesicle, I consider it better than taking it direct from the cow, for the following reasons: The cow-pox lymph, taken direct from the cow, produces much more violent symptoms than after it has passed through several persons; indeed, in some cases, it has produced effects as severe as cutting for the small-pox, besides, it has caused, in many cases, violent inflammation and even sloughing of the arm.

They all assume the ordinary cell character, with outer and inner sac, the inner sac forming on the side, like the Purkinjean vesicle itself; but it does not retain this position, for, as soon as its wall is formed and it becomes a distinct body, it floats away from the side and takes its place in the centre.

The Gastraea itself has originated from the simple multicellular vesicle, the Blastaea, and this in turn must have been evolved from the lowest circle of unicellular animals, to which we give the name of Protozoa. We have already considered the most important primitive type of these, the unicellular Amoeba, which is extremely instructive when compared with the human ovum.

Now this is actually so: in some the auricle presents itself as a sanguinolent vesicle, as a thin membrane containing blood, as in fishes, in which the sac that stands in lieu of the auricles is of such delicacy and ample capacity that it seems to be suspended or to float above the heart.

They all took the infection, and either on the fifth or sixth day a vesicle was perceptible on the punctured part. Some of them began to feel a little unwell on the eighth day, but the greater number on the ninth.

If you turn to the production of the chick in ovo, however, you will find at first no more a vesicle or auricle, or pulsating drop of blood; it is only by and by, when the development has made some progress, that the heart is fashioned; even so in certain animals not destined to attain to the highest perfection in their organization, such as bees, wasps, snails, shrimps, crayfish, etc., we only find a certain pulsating vesicle, like a sort of red or white palpitating point, as the beginning or principle of their life.