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It was soon manifest that the secretion of the gland was dependent upon the iodine content for its activity. Active extracts of the thyroid like thyreoglobulin and iodothyrin were proven to contain iodine, and to become inactive when the iodine was removed. Efforts to isolate the iodine containing active principle in pure form were fruitless until the work of Kendall at the Mayo Foundation.

The Relationship of Maternal and Sexual Emotion Conception and Loss of Virginity The Anciently Accepted Signs of This Condition The Pervading Effects of Pregnancy on the Organism Pigmentation The Blood and Circulation The Thyroid Changes in the Nervous System The Vomiting of Pregnancy The Longings of Pregnant Women Maternal Impressions Evidence for and Against Their Validity The Question Still Open Imperfection of Our Knowledge The Significance of Pregnancy.

The increased action of the muscles of the heart and the blood-vessels increases the efficiency of the circulation; the secretion of the adrenal gland causes a rise in the blood-pressure; the increased action of the thyroid gland causes an increased metabolic activity; there is evidence that glycogen is actively called out, this being the most immediately available substance for the production of energy; the increased activity of the respiration is needed to supply the greater need of oxygen and the elimination of the increased amount of waste products; the dilatation of the nostrils affords a freer intake of air; the increased activity of the sweat-glands is needed to regulate the temperature of the body which the increased metabolism causes to rise.

It is thought by some authorities that the thyroid gland has to do with the control of the excretion of the waste products from nitrogenous foods, for it has been found that a meat diet or a high-proteid diet is extremely harmful in disorders of this organ.

As regards the seeming function of the thyroid, it may be said that the surviving relic of an ancient functional organ is quite capable of varying in structure and taking upon itself a new function, of minor value, which in its absence would be left undone or be performed by some of the other organs.

Some students of the subject conclude that the function of the thyroid gland is to destroy poisonous products formed by the decomposition of proteid food substances. It is believed by others that it also has a defensive action against other poisons in the body, including alcohol and poisonous drugs. In other words, it is thought to have an "antitoxic" action.

The most important of the ductless glands are the thyroid gland, located in the neck; the suprarenal bodies, situated one just over each kidney; and the thymus gland, a temporary gland in the upper part of the chest. They perform in this way a function like that of the ductless glands. The work of glands in preparing substances that enter the blood is known as internal secretion.

So it has been discovered that during the winter months, the thyroid glands of beef, sheep and hogs all contain much less iodine than during the summer months. During the winter months, manifestly, more energy is required to maintain body temperature, hence the gland surrenders more of its secretion to the tissues and so keeps less of it itself.

Scientific men while delving into the marvelous secrets of physiology, have learned that the thyroid gland in some peculiar manner possesses an extraordinary influence upon vital stamina and virility.

The characteristics of this form of idiocy are an enlarged thyroid gland constituting a goitre or bronchocele, a high-arched palate, dwarfed stature, squinting eyes, sallow complexion, small legs, conical head, large mouth, and indistinct speech. Feeble-mindedness may affect the moral nature only, rendering the person selfish, untruthful, obscene, or unemployable.