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Longuet regards the condition of the blood in leukemia as the cause of such priapism, and considers that the circulation of the blood is retarded in the smaller vessels, while, owing to the great increase in the number of white corpuscles, thrombi are formed. Neidhart and Matthias conclude that the origin of this condition might be sought for in the disturbance of the nerve-centers.

#Embolism.# The term embolus is applied to any body carried along in the circulation and ultimately becoming impacted in a blood vessel. This occurrence is known as embolism. The commonest forms of embolus are portions of thrombi or of fibrinous formations on the valves of the heart, the latter being usually infected with micro-organisms.

In other cases thrombosis is associated with certain constitutional diseases gout, for example; the endothelium of the veins undergoing changes possibly the result of irritation by abnormal constituents in the blood which favour the formation of thrombi.

Thrombi usually originate in venous cysts or pouches, and at acute bends on the vessel, especially when these are situated in the vicinity of the knee, and are subjected to repeated injuries for example in riding. Phleboliths sometimes form in such pouches, and may be recognised in a radiogram.

On post-mortem examination the lesions found in these cases are: general hyperæmia of all the organs of the abdominal, thoracic, and cerebro-spinal cavities; marked leucocytosis, with destruction of red corpuscles, setting free hæmoglobin which lodges in the epithelial cells of the tubules of the kidneys; minute thrombi and extravasations throughout the tissues of the body; degeneration of the ganglion cells of the solar plexus; œdema and degeneration of the lymphoid tissue throughout the body; cloudy swelling of the liver and kidneys, and softening and enlargement of the spleen.