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Hæmorrhage may take place from a varicose vein as a result of a wound or of ulceration of its wall. Increased intra-venous pressure produced by severe muscular strain may determine rupture of a vein exposed in the floor of an ulcer.

Sclerosis of the meshwork of the iris angle is the predisposing factor because it hinders free access of aqueous into the venous sinus of Schlemm. Sclerosis alone, however, will not cause glaucoma so long as access to the iris veins can keep the intra-ocular pressure at the intra-venous level, and, too, as long as the exciting cause is absent.

To prevent bleeding in hæmophilics, intra-venous or subcutaneous injections of fresh blood serum, taken from the human subject, the sheep, the dog, or the horse, have proved useful. If fresh serum is not available, anti-diphtheritic or anti-tetanic serum or trade preparations, such as hemoplastin, may be employed.

The quantity of toxin circulating in the blood is so small as to be practically negligible, and the risk of anaphylactic shock attending intra-venous injection outweighs any benefit likely to follow this procedure.

The Government under these circumstances would pay the expenses of a wife or mother to come over and say the last good-bye. After the message went, it seemed that our friend could not last till their arrival, and the colonel decided as a last chance to try intra-venous injections of Eusol, the powerful antiseptic in use at that time in all the hospitals.

No ulcerative process responds so readily to medicinal treatment as the syphilitic ulcer does to the intra-venous administration of arsenical preparations of the "606" or "914" groups or to full doses of iodide of potassium and mercury, and the local application of black wash.

To summarize: The aqueous has direct access to the anterior uveal venous system; the physiological thickening of the strands of the meshwork of the iris angle supplies a mechanical obstruction between the anterior chamber and the venous sinus of Schlemm; intra-ocular pressure stands at the same level as the intra-venous, consequently, the hydrostatic pressure is the same on both sides of the iris angle meshwork, because the canal of Schlemm is a secondary venous system; lastly, the outflow of aqueous into the venous sinus is by diffusion, not by filtration, because the pressure is the same on both sides of the meshwork.