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Other results of uric acid irritation are: inflammatory and catarrhal conditions of the bronchi, lungs, stomach, intestines, genitourinary organs; rapid pulse; palpitation of the heart; angina pectoris; etc.

John Waterman, a resident of Fishertown, near Salisbury, England, who gave birth to a double female monster on October 26, 1664, which evidently from the description was joined by the ischii. It did not nurse, but took food by both the mouths; all its actions were done in concert; it was possessed of one set of genitourinary organs; it only lived a short while.

These poisonous drugs relieve the cough and the catarrhal conditions by paralyzing the eliminative activity of the membranous linings of the nasal passages, the bronchi and lungs, the digestive and genitourinary organs; but in doing so, they throw back into the system the morbid matter which Nature is trying to get rid of, and add drug poisons to disease poisons.

If, however, the organism is already overloaded with waste and morbid materials, if the bowels and the kidneys are already weakened and atrophied through continued overwork and overstimulation, if, in addition to this, the vitality has been lowered through excesses or overexertion and the vital fluids are in an abnormal condition, then the morbid matter thrown into the circulation by the chilling and temporary inactivity of the skin cannot find an outlet through the regular channels of elimination and endeavors to escape by way of the mucous linings of the nasal passages, the throat, bronchi, stomach, bowels and genitourinary organs.

This is what takes place: The morbid matter and poisons thrown off by the cells and tissues are carried by means of the venous circulation to the organs of elimination, the bowels, kidneys, lungs and skin, and to the mucous membranes lining the interior tracts, such as the nasal passages, the throat and bronchi, the digestive and genitourinary canals, etc.

The Ephemerides speaks of a case of coalition of the bladder with the os pubis and another case of coalition with the omentum. Prochaska mentions vesical fusion with the uterus, and we have already described union with the rectum and intestine. Exstrophy of the bladder is not rare, and is often associated with hypospadias, epispadias, and other malformations of the genitourinary tract.