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Crepitation or a grinding, rubbing sound due to the movement of the ends of the broken bones on one another occurs when the part is moved or manipulated with the hands. Pain, swelling and injury to the skin are other local symptoms. The new tissue or bone callus is formed by the bone-forming cells in the deeper layer of the periosteum and bone-marrow. The prognosis is unfavorable.
In bacterial diseases originating in the marrow, if the epiphysial junction is directly involved in the destructive process, its bone-forming functions may be retarded or abolished, and the subsequent growth of the bone be seriously interfered with.
The epiphysial cartilage usually continues its bone-forming functions, but when it has been seriously damaged or displaced, the further growth of the bone in length may be interfered with. Sometimes the separated and displaced epiphysis dies and constitutes a sequestrum. The adjacent joint may become filled at an early stage with a serous effusion, which may be sterile.
There is a wide division between facts thus learnt off glibly at school and the practical application of them to our daily wants. The human body, if it is to be maintained in but a fair state of health, requires a certain amount of fresh air a certain amount of flesh-forming, bone-forming, brain-forming, and warmth-giving nutriment.
On the other hand, if it is not directly involved but is merely influenced by the proximity of an infective focus, its bone-forming functions may be stimulated by the diluted toxins and the growth of the bone in length exaggerated. In paralysed limbs the growth from the epiphyses is usually little short of the normal.
Then they must have lived under favorable conditions, had plenty of flesh and bone-forming food, and after several generations they gradually grew larger. You know that by feeding the right kind of food to animals you can make them bigger, while if they get the wrong kind they are runts, or dwarfs." "Oh, yes; that's a well-known fact," chimed in Mr. Damon.
In a few minutes Ancrum found himself buried in 'details' as to 'flesh-forming' and 'bone-forming' foods, as to nitrogen and albumen, as to the saving qualities of fruit, and Heaven knows what besides. Long before the enthusiast had spent his breath or his details, the minister cried 'Enough!
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