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The first fall of temperature which follows division of the cord is believed by most physiologists to be due to this dilatation of the vessels. Very probably the blood-stream, flowing sluggishly, does not give the normal amount of stimulus to the tissues, so that at first their chemical actions are lessened, and consequently less caloric than usual is generated in the body.

For the conscience a diet of white flour and water may be all right, but Jimmie soon found that it is very bad indeed for the intestinal tract and the blood-stream being, in truth, far worse than a diet of water alone.

#Teno-synovitis.# The toxic or infective agent is conveyed to the tendon sheaths through the blood-stream, as in the gouty, gonorrhœal, and tuberculous varieties, or is introduced directly through a wound, as in the common pyogenic form of teno-synovitis. Teno-synovitis Crepitans.

The malignancy of cancer depends on the tendency which the epithelium has of invading the tissues in its neighbourhood, and on the capacity of the cells, when transported elsewhere by the lymph or blood-stream, of giving rise to secondary growths.

In the human subject, multiplication in the blood-stream does not occur to any great extent. In some general acute pyogenic infections, such as osteomyelitis, cellulitis, etc., pure cultures of staphylococci or of streptococci may be obtained from the blood. In pneumococcal and typhoid infections, also, the organisms may be found in the blood.

PYOGENIC DISEASES OF BONE. These diseases result from infection with pyogenic organisms, and two varieties or types are recognised according to whether the organisms concerned reach their seat of action by way of the blood-stream, or through an infection of the soft parts in contact with the bone.

If he can destroy the bacillus and survive, so much the better; but if not, he will simply overwhelm him by the weight of his body-mass, and be swept on through the blood-stream into the great body-sewers, with the still living bacillus literally buried in his dead body.

Sometimes the thrombus is mixed a red thrombus being deposited on a white one, it may be in alternate layers. When aseptic, a thrombus may become detached and be carried off in the blood-stream as an embolus; it may become organised; or it may degenerate and undergo calcification.

Fragments of the parent tumour may become separated and be carried off in the lymph or blood-stream and deposited in other parts of the body, where they give rise to secondary growths. Malignant tumours tend to invade and destroy the overlying skin or mucous membrane, and thus give rise to bleeding ulcers; if the tumour tissue protrudes through the gap in the skin, it is said to fungate.

Every part of the body is brought into common life with every other part by this impetuous blood-stream which is here, there, and everywhere, right round, and back again, in twenty-five seconds!